Its formula, boosted with lightening agents twice as concentrated as those in Crème PIGM 400 provides a super-effective response to inhibited melanin synthesis.
The PIGM 400 range has complex formulas designed to prevent and fade all types of pigment irregularities by reducing the size, maturation cycle and migration of pigment-producing cells. ⠀
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The PIGM 400 range also works by preventing tyrosinase, the enzyme responsible for the production of melanin. Besides, its photo-protective and anti-free radical agents slow skin ageing.
Apply Sérum PIGM 400 before Crème PIGM 400, in the morning and/or evening on the entire face to illuminate the complexion and/or topically on the dark spots (face, forearms, cleavage and hands).
Cautions: Protect the skin from the sun during the use of the product.
Watercress Sprout Extract and Soy-based Pure Genistin: This extract regulates the formation of melanin and lipofuscin and reduces their accumulation in the skin by activating proteasome. It reduces the pigmentation of brown spots in a targeted way(in vivo), prevents photo-induced aging and evens out skin pigmentation(in vivo).
Plum Pulp Extract: Plum pulp is known for its lightening properties (in vivo): it limits melanogenesis by inhibiting melanin phagocytosis by keratinocytes (in vitro). It also improves the skin’s barrier effect, increases hydration (reducing Trans Epidermal Water Loss –in vivo) and improves the skin’s structure (in vivo).
Sea Lily Extract: Sea Lily Extract is a lightening agent (in vivo): it inhibits melanogenesis by reducing the dendricity of the melanocytes (in vitro) and by inhibiting the synthesis of Substance P receptors on the surface of the dendrites (in vitro). It also inhibits the expression of POMC (protein precursor of α-MSH) and the synthesis of intracellular melanin. As a result, there is a reduction in the size of dendrites, the size of pigmented spots, and in the coloration of spots.
Sea Fern(Seaweed) Extract: This is a lightening agent (in vivo) that also helps reduce the size of pigmented spots (in vivo): It controls the number, size and maturation of melanosomes (in vitro), inhibits the activation of melanogenesis by endothelin (in vitro) and the activation of tyrosinase by gene MITF (in vitro), as well as the expression of genes involved in the migration, production and exportation of melanin (in vitro).
Wasabi Extract: Wasabi is a Japanese plant (of the Brassica family) that only grows in rivers with very pure water. Wasabi is known for its antiseptic properties (in vitro) thanks to the three families of molecules making it up (oxidoreductases, isocyanates, glucosinolates).It traps and neutralizes certain free radicals (in vitro).
